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Barriers and enablers to medicine-taking behaviours in chronic obstructive pulmonary disease: a qualitative interview study

Lookup NU author(s): Professor Hamde NazarORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Abstract

© The Author(s) 2025.Background: Chronic Obstructive Pulmonary Disease (COPD) is associated with low health-related quality of life and high costs to healthcare systems, particularly due to hospital admissions and exacerbations. Medicines, inhalers especially, reduce the risk of hospitalisations and exacerbations, but factors influencing medicine-taking behaviours are not fully understood. Aim: To explore experiences of people with COPD related to medicines, and followingly identify and characterise any barriers and enablers related to medicine-taking behaviours using the Theoretical Domains Framework (TDF). Method: Semi-structured qualitative interviews were conducted and included ten people with COPD who had previously been admitted to hospital. Systematic text condensation was used inductively in the primary analysis of the interviews. In the secondary analysis, meaning units from the primary analysis were mapped to the TDF and summarised as barriers and enablers. Results: Five major themes were developed in the primary analysis: (1) health literacy and information needs, (2) patient autonomy, (3) lack of access to medicines, (4) lack of effect from medicines, and (5) experiences of medicines-related issues. In the secondary analysis, thirteen barriers and nine enablers were mapped to nine out of the fourteen domains of the TDF. Conclusion: People with COPD experience challenges related to medicines which need to be addressed by researchers and healthcare providers. The identified barriers and enablers mapped to the TDF can guide and inform future design of interventions and health care services.


Publication metadata

Author(s): Nygard T, Wright D, Kjome RLS, Nazar H, Aarli B, Raddum A

Publication type: Article

Publication status: Published

Journal: International Journal of Clinical Pharmacy

Year: 2025

Volume: 47

Pages: 775-783

Print publication date: 01/06/2025

Online publication date: 05/02/2025

Acceptance date: 17/01/2025

Date deposited: 03/03/2025

ISSN (print): 2210-7703

ISSN (electronic): 2210-7711

Publisher: Springer

URL: https://doi.org/10.1007/s11096-025-01872-9

DOI: 10.1007/s11096-025-01872-9


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Funding

Funder referenceFunder name
Norwegian Foundation for Pharmacy Practice Research
University of Bergen (incl Haukeland University Hospital)

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