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A United Kingdom Value Set for the Weight-Specific Adolescent Instrument for Economic Evaluation

Lookup NU author(s): Tomos RobinsonORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Abstract

© 2025Objectives: The Weight-Specific Adolescent Instrument for Economic Evaluation (WAItE) is a weight-specific patient-reported outcome measure for use in adolescence, consisting of 7 domains, each with 5 response levels. The objective of this study was to generate a UK value set for the WAItE, enabling the calculation of utility values. Methods: An online discrete choice experiment (DCE) completed by an adult sample representative of the working population of the United Kingdom was used to estimate the preferences for the 5 levels of the 7 domains. DCE data were analyzed using multinomial and mixed logit models. The latent values were then anchored onto the 0-1 death-full health quality-adjusted life year scale using 2 different anchoring techniques, the time trade-off method and the DCE-visual analog scale method. Results: A total of 1004 adults from the United Kingdom were included in the final estimation sample for the DCE. From the latent estimates, the majority of the levels of the dimensions followed the monotonic nature of the WAItE; however, some levels of the Tiredness-, Walking-, and Sports-related dimensions were not monotonic and combined to generate the final value set. The results from the time trade-off and DCE-visual analog scale anchoring methods were similar, with values for the PITS state (the worst health state possible from the WAItE) of 0.289 and 0.230. Conclusions: This study has developed a value set for the WAItE based on the preferences of the UK population, enabling the use of the WAItE in cost-utility analyses of interventions targeting obesity in adolescents.


Publication metadata

Author(s): Robinson T, Hill S, Oluboyede Y

Publication type: Article

Publication status: Published

Journal: Value in Health

Year: 2025

Volume: 28

Issue: 4

Pages: 633-642

Print publication date: 01/04/2025

Online publication date: 27/01/2025

Acceptance date: 06/01/2025

Date deposited: 04/03/2025

ISSN (print): 1098-3015

ISSN (electronic): 1524-4733

Publisher: Elsevier Ltd

URL: https://doi.org/10.1016/j.jval.2025.01.002

DOI: 10.1016/j.jval.2025.01.002

PubMed id: 39880199


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Funding

Funder referenceFunder name
National Institute for Health and Care Research Public Health Research Programme (NIHR127745)

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