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Lookup NU author(s): Dr Yincent TseORCiD, Nicola Vasey, Dr Rhys ThomasORCiD, Dr Suzy Leech, Dr Stephen Owens, Professor John SayerORCiD
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© Author(s) (or their employer(s)) 2025.Paediatricians across many specialities and pharmacists are increasingly being asked to prescribe, or jointly look after, children treated with mammalian target of rapamycin (mTOR) inhibitors (eg, sirolimus and everolimus). There is an expanding list of conditions including tuberous sclerosis and vascular malformations where treatment with mTOR inhibitors may help. This brief practice pointer summarises the practical steps before starting these treatments, what potential side effects to discuss with families and what monitoring arrangements should be put in place.
Author(s): Tse Y, Vasey N, Thomas R, Leech S, Owens S, Sayer J
Publication type: Article
Publication status: Published
Journal: Archives of Disease in Childhood: Education and Practice Edition
Year: 2025
Pages: epub ahead of print
Online publication date: 16/02/2025
Acceptance date: 31/01/2025
ISSN (print): 1743-0585
ISSN (electronic): 1743-0593
Publisher: BMJ Publishing Group
URL: https://doi.org/10.1136/archdischild-2024-327852
DOI: 10.1136/archdischild-2024-327852
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