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A systematic review of SARS-CoV-2 associated sudden onset sensorineural hearing loss

Lookup NU author(s): Dr Ben Talks, Nick Dawe, Dr Michael Mather

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Abstract

© 2025 Cambridge University Press. All rights reserved.Introduction: Sudden onset sensorineural hearing loss (SSNHL) has been associated with infection by SARS-CoV-2. However, little is known regarding how this differs from SSNHL of other aetiologies. This systematic review summarises existing literature on SARS-CoV-2 associated SSNHL treatment and outcomes. Methods: A literature search using Ovid was performed for studies which evaluated treatments and outcomes of patients with SSNHL associated with SARS-CoV-2 infection. Results: 99 studies were identified, from which 14 studies were selected for inclusion - collectively including 154 patients. Nine of these studies were single participant case reports and five were larger case series. Corticosteroid treatment varied between studies in terms of administration route, dose, and duration. Only 63/154 patients in this review achieved complete resolution of their symptoms following steroid treatment. Conclusion: Oral, intravenous, and intratympanic steroids demonstrate a good safety profile. However, the majority of patients are left with unresolved hearing loss.

Publication metadata

Author(s): Fouweather M, Talks B, Dawe N, Mather MW

Publication type: Article

Publication status: Published

Journal: Journal of Laryngology and Otology

Year: 2025

Volume: 139

Issue: 7

Pages: 528-534

Online publication date: 04/04/2025

Acceptance date: 02/04/2025

ISSN (print): 0022-2151

ISSN (electronic): 1748-5460

Publisher: Cambridge University Press

URL: https://doi.org/10.1017/S002221512500026X

DOI: 10.1017/S002221512500026X

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