ePrints

Crystallographic Combinations: Understanding Polymorphism and Approximate Symmetry in N-(1,3-thiazol-2-yl)benzamide

Lookup NU author(s): Dr Michael HallORCiD, Dr Paul Waddell

Downloads

• Published version [.pdf]

Licence

This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Abstract

A new polymorph of N-(1,3-thiazol-2-yl)benzamide crystallizes in the monoclinic space group Pc with four crystallographically-independent molecules (Z′ = 4) in the asymmetric unit. Where the previously reported polymorphs exhibit two distinct hydrogen-bonded dimer geometries exclusively, the asymmetric unit of the new polymorph comprises both. Approximate symmetry was observed to relate the molecules of these dimers. These approximate symmetry elements combine to form a structure with distorted P2₁/c space group symmetry, rationalising the unexpectedly high number of crystallographically-independent molecules.

Publication metadata

Author(s): Voigt JC, Hall MJ, Waddell PG

Publication type: Article

Publication status: Published

Journal: Crystals

Year: 2025

Volume: 15

Issue: 7

Print publication date: 01/07/2025

Online publication date: 18/07/2025

Acceptance date: 16/07/2025

Date deposited: 23/07/2025

ISSN (electronic): 2073-4352

Publisher: MDPI AG

URL: https://doi.org/10.3390/cryst15070657

DOI: 10.3390/cryst15070657

Data Access Statement: CCDC 2457230 contains the full crystallographic data for this article. These are available free of charge at www.ccdc.cam.ac.uk/data_request/cif (accessed on 15 July 2025), by emailing data_request@ccdc.cam.ac.uk or by contacting the Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge, CB2 1EZ, UK; Fax: +44-1223-336033.

Altmetrics

Share