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Lookup NU author(s): Jess Page, Dr Owen JeffriesORCiD
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
Caffeine and taurine are commonly co-ingested pre-exercise but elicit different thermoregulatory responses; however, their combined effect on thermoregulation is unknown. Therefore, we evaluated the effects of oral caffeine and taurine co-ingestion on time to exhaustion (TTE) and thermoregulatory responses to cycling in the heat at the gas exchange threshold (GET). Ten healthy nonheat acclimated participants took part in a double-blind crossover study, completing a TTE in the heat (35°C; 40% relative humidity), cycling at a power output associated with the GET and 1 h after ingesting: caffeine (5 mg/kg) and taurine (50 mg/kg) combined or placebo. Pulmonary gas exchange, core and mean skin temperatures and whole-body sweat rate (WBSR) were recorded throughout. Heat production was determined using partitional calorimetry. There were no differences in TTE between conditions (p = 0.608); however, the rate of oxygen consumption (p = 0.017), minute ventilation (p = 0.029) and heat production (p = 0.019) were higher following the supplement. There were no differences between conditions for skin (p = 0.539) and core temperature (p = 0.699), mean skin blood flow (p = 0.119), respiratory exchange ratio (p = 0.546) and WBSR (p = 0.897). Pre-exercise co-ingestion of caffeine and taurine in the heat had no ergogenic effect despite increasing the ventilatory and metabolic demand. Collectively, these data indicate minimal effects on whole-body thermoregulation.
Author(s): Aggett J, Page J, Peel J, John K, Matta G, Tallent J, Heffernan S, Jeffries O, Waldron M
Publication type: Article
Publication status: Published
Journal: European Journal of Sport Science
Year: 2025
Volume: 25
Issue: 10
Print publication date: 01/10/2025
Online publication date: 16/09/2025
Acceptance date: 18/08/2025
Date deposited: 10/09/2025
ISSN (print): 1746-1391
ISSN (electronic): 1536-7290
Publisher: John Wiley and Sons Inc
URL: https://doi.org/10.1002/ejsc.70044
DOI: 10.1002/ejsc.70044
Data Access Statement: All data are available upon reasonable request.
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