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Lookup NU author(s): Dr Clement LeeORCiD
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
Aim: To determine if perceptual speech measures distinguish people with Parkinson’s disease (PD), multiple system atrophy with predominant parkinsonism (MSA-P) and progressive supranuclear palsy (PSP). Methods: Speech–language therapists blind to patient characteristics employed clinical rating scales to evaluate speech/voice in 24 people with clinically diagnosed PD, 17 with PSP and 9 with MSA-P, matched for disease duration (mean 4.9 years, standard deviation 2.2). Results: No consistent intergroup differences appeared on specific speech/voice variables. People with PD were significantly less impaired on overall speech/voice severity. Analyses by severity suggested further investigation around laryngeal, resonance and fluency changes may characterize individual groups. Conclusion: MSA-P and PSP compared with PD were distinguished by severity of speech/voice deterioration, but individual speech/voice parameters failed to consistently differentiate groups.
Author(s): Lee C, Battiston M
Publication type: Article
Publication status: Published
Journal: Journal of Computational and Graphical Statistics
Year: 2025
Volume: 7
Issue: 13
Pages: 191-203
Online publication date: 04/09/2025
Acceptance date: 22/08/2025
Date deposited: 30/09/2025
ISSN (print): 1061-8600
ISSN (electronic): 1537-2715
Publisher: Taylor & Francis
URL: https://doi.org/10.1080/10618600.2025.2554680
DOI: 10.1080/10618600.2025.2554680
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