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Deciphering the role of complement system genes in pancreatic cancer susceptibility and prognosis

Lookup NU author(s): Professor Linda SharpORCiD

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Author(s): Langtry A, Rabadan R, Alonso L, Filip I, Lawlor R, Carrato A, Alvarez-Gallego R, Iglesias M, Molero X, Lohr MJ, Michalski CW, Perea J, Barbera VM, Tardon A, Farre A, Munoz-Bellvis L, Crnogorac-Jurcevic T, Dominguez-Munoz E, Gress TM, Greenhalf W, Sharp L, Balsells J, Costello E, Kleeff J, Kong B, Mora J, O'Driscoll D, Scarpa A, Ye W, Real FX, Lopez de Maturana E, Malats N, Alonso L, Sabroso-Lasa S, Sabroso-Lasa S, Moreno-Oya A, Moreno-Oya A, Gomez-Rubio P, Molina-Montes E, Marquez M, Milne R, Alfaro A, Lobato T, Estudillo L, Real FX, Malats N, Scarpa A, Beghelli S, Cubillo A, Hidalgo M, Peinado P, Salas I, Rodriguez Pascual J, Earl J, Caminoa A, Guillen-Ponce C, Rodriguez-Garrote M, Longo-Munoz F, Ferreiro R, Pachon V, Vaz MA, Munoz M, Ilzarbe L, Alvarez-Urturi C, Bessa X, Bory F, Marquez L, Poves I, Burdio F, Grande L, Gimeno J, Guarner L, Balcells J, Salcedo M, Merino X, Esposito I, Kleeff J, Kong B, Mota C, Lohr MJ, Huang J, Verbeke C, Ye W, Yu J, Loinaz C, Perea J, Rodriguez-Peralto JL, Teijo A, Pelaez P, Martin M, Artigas V, Guarner C, Sancho FJ, Concepcion M, Ramon y Cajal T, Szafranska J, O'Rorke M, O'Rorke M, Murray L, Cantwell M, Gallego J, Tardon A, Barneo L, Rodriguez-Suarez MM, Pazos Y, Lozano A, Luaces M, Blanco-Antona F, Sayagues Manzano JM, Gutierrez Troncoso ML, Orfao de Matos A, Munoz-Bellvis L, Gress TM, Buchholz M, Neesse A, Costello E, Kocher HM, Bhattacharya S, Abraham AT, Ennis D, Dowe T, Radon T

Publication type: Article

Publication status: Published

Journal: Nature Communications

Year: 2025

Volume: 16

Issue: 1

Online publication date: 28/11/2025

Acceptance date: 23/10/2025

Date deposited: 16/12/2025

ISSN (electronic): 2041-1723

Publisher: Nature Research

URL: https://doi.org/10.1038/s41467-025-65811-y

DOI: 10.1038/s41467-025-65811-y

Data Access Statement: No custom code or mathematical algorithms were developed for this study. All analyses were performed using publicly available software and packages, as described in the Methods section. Data availability - see paper https://doi.org/10.1038/s41467-025-65811-y

PubMed id: 41315260


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Funder referenceFunder name
NIH (R35 CA253126.)

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