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Stenting versus shunting in sight-threatening idiopathic intracranial hypertension: genuine equipoise

Lookup NU author(s): Professor Phil WhiteORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Abstract

© Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY. Published by BMJ Group. This opinion piece discusses the challenges of managing a person with sight-threatening papilloedema due to idiopathic intracranial hypertension (IIH). With no available randomised controlled trials, clinicians often choose locally available surgical intervention. An increasing number of studies have advocated using dural venous sinus stenting in IIH. Big data studies show that shunts have been the mainstay of surgical treatment for IIH, and recent evidence shows improved outcomes and fewer revision surgeries. There remains genuine equipoise in the choice of intervention between shunting and dural venous stenting in IIH. The IIH Intervention Trial funded by the National Institute of Health Research is underway in the UK, the first randomised control trial to evaluate both of these surgical interventions in people with sight-threatening IIH.


Publication metadata

Author(s): Mollan SP, Tsermoulas G, Berman G, Toma AK, Fergus R, White P, Wakerley BR, Sinclair AJ

Publication type: Article

Publication status: Published

Journal: Practical Neurology

Year: 2025

Pages: Epub ahead of print

Online publication date: 09/12/2025

Acceptance date: 05/11/2025

Date deposited: 22/12/2025

ISSN (print): 1474-7758

ISSN (electronic): 1474-7766

Publisher: BMJ Publishing Group

URL: https://doi.org/10.1136/pn-2025-004728

DOI: 10.1136/pn-2025-004728

Data Access Statement: No data are available.


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Funding

Funder referenceFunder name
NIHR - NIHR131211 - Intervention To Preserve Vision In Idiopathic Intracranial Hypertension: Evaluation Of Clinical Effectiveness And Cost Effectiveness

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