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HiSNAP trial-a multicentre, randomised, open-label, blinded end point, safety and efficacy trial of conventional (300 mg/kg) versus higher doses of acetylcysteine (450 mg/kg and 600 mg/kg) in patients with paracetamol overdose in the UK: study protocol

Lookup NU author(s): Dr Ruben ThanacoodyORCiD

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Author(s): Humphries C, Clarke E, Eddleston M, Gillings M, Irvine S, Keating L, Miell A, Milne L, Muir L, O'Brien R, Oatey K, Raman R, Thanacoody R, Tuck S, Weir CJ, Wood DM, Dear JW

Publication type: Article

Publication status: Published

Journal: BMJ Open

Year: 2025

Volume: 15

Online publication date: 22/03/2025

Acceptance date: 30/01/2025

Date deposited: 06/01/2026

ISSN (print): 2044-6055

ISSN (electronic): 2044-6055

Publisher: BMJ Publishing Group

URL: https://doi.org/10.1136/bmjopen-2024-097432

DOI: 10.1136/bmjopen-2024-097432

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