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Change In Bone Mineral Density After Total Ankle Replacement: A Two Year Follow Up [التغير في كثافة العظام المعدنية بعد استبدال الكاحل الكلي - متابعة لمدة عامين]

Lookup NU author(s): Malik Siddique

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Abstract

© 2026 DSR Publishers/The University of Jordan. All Rights Reserved. Background: Bone strength around the components is critical for arthroplasty survival. Literature is scarce on changes in bone mineral density (BMD) around total ankle arthroplasty (TAA) designs. This study quantified BMD changes around the components of the uncemented Mobility™ prosthesis preoperatively and postoperatively, while evaluating clinical outcomes. Methods: This prospective study included patients undergoing TAA between March 2008 and April 2009. BMD was measured using the DEXA Hologic® scanner at seven regions of interest (ROIs) around the prosthesis preoperatively and at 1-and 2-year follow-ups. AOFAS scores were also recorded. Results: Twenty-three patients were included. A significant mean BMD decrease (17%, p<0.01) was observed in the lateral malleolus, while the medial tibial metaphysis showed a 7% increase, though not statistically significant. BMD changes at other ROIs were minimal. AOFAS scores improved significantly over the 2 years (p<0.05). Conclusion: Significant BMD loss occurred in the lateral malleolus, likely due to stress shielding. Minimal changes in other regions suggest a stable mechanical environment. Long-term follow-up is necessary to determine the clinical impact of these changes.


Publication metadata

Author(s): Alkhreisat M, Battah K, Ramas Ramaskandhan J, Al Ananzh M, Siddique M

Publication type: Article

Publication status: Published

Journal: Jordan Medical Journal

Year: 2026

Volume: 60

Issue: 1

Pages: 68-77

Online publication date: 01/02/2026

Acceptance date: 02/04/2018

ISSN (print): 0446-9283

ISSN (electronic): 2664-8091

Publisher: Deanship of Scientific Research, University of Jordan

URL: https://doi.org/10.35516/jmj.v60i1.3858

DOI: 10.35516/jmj.v60i1.3858


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