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Clinical Trial Landscape: An Analysis of Obesity and Overweight Clinical Trials in the Past Year

Lookup NU author(s): Cyril Onwuelazu UtehORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Abstract

Background and Aims: Obesity and overweight are a worldwide problem, affecting people of all age and race. In 2022, around 16% of adults globally were obese. Also, roughly 35 million children below age five were overweight in 2024, and about 50% of these obese or overweight children lived in Asia. This study, therefore, investigated the clinical trial landscape for obesity and overweight in the last one year. Methods: A search of clinical trials (CT) on obesity and overweight was conducted on ClinicalTrials.gov database between July – September 2025, to identify CTs first posted between the 1st of September 2024 and the 7th of September 2025 (date of last search). The search outputs were screened based on developed inclusion and exclusion criteria. See Table 1 for the screening processes and inclusion/exclusion criteria. Results: A total of 267 CTs on obesity and overweight with an estimated 76074 participants were identified and analysed. Roughly 50% (134/267) of the CTs are still recruiting participants, while around 24% (64/267) are not yet recruiting. Only about 6% (17/267) of the CTs, recruited child participants. About 52% (139/267) and 36% (95/267) of the CTs included locations in North America and Asia respectively. Other CT locations included Africa, Europe, Oceania and South America. Conclusions: The higher CT locations in North America and Asia reflected the burden of obesity and overweight in these regions. More CTs on obesity and overweight in children are recommended. This study was limited to CTs published on Clin-icalTrials.gov and does not generalise across all CT databases.


Publication metadata

Author(s): Uteh CO

Publication type: Conference Proceedings (inc. Abstract)

Publication status: Published

Conference Name: Advanced Technologies and Treatments for Diabetes Asia (ATTD-ASIA) Conference

Year of Conference: 2025

Pages: 351S-351S

Online publication date: 09/03/2026

Acceptance date: 09/03/2026

Date deposited: 19/03/2026

ISSN: 1557-8593

Publisher: SAGE Publications

URL: https://doi.org/10.1177/15209156251412178

DOI: 10.1177/15209156251412178

ePrints DOI: 10.57711/5y2m-qf23

Series Title: Diabetes Technology & Therapeutics


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