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Endotracheal surfactant for infants with life-threatening bronchiolitis (BESS): a randomised, blinded, sham-controlled, phase 2 trial

Lookup NU author(s): Dr Rachel Agbeko

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Publication metadata

Author(s): Semple MG, Donohue C, Price L, Cooper R, Vaughan C, Moitt T, Finnetty L, Ritson PC, Osaghae B, Allen E, Fowler C, Agbeko RS, Brincat E, Cassidy JV, Davies PE, Davis PJ, Day E, Kanaris C, Lampariello S, Levin R, Lo T-YM, Morris KP, Osman A, Playfor SD, Richardson J, Sefton G, Sundararajan S, Weitz J, Wherton-Whitehurst A, Deja E, Woolfall K, Madsen J, Postle AD, Barker C, Gamble C, Clark HW, Pappachan J, Thorburn K, Peak M, McNamara PS, Turner MA, Jones AP, BESS Investigators

Publication type: Article

Publication status: Published

Journal: The Lancet Respiratory Medicine

Year: 2026

Pages: epub ahead of print

Online publication date: 21/03/2026

Acceptance date: 02/04/2025

Date deposited: 14/04/2026

ISSN (print): 2213-2600

ISSN (electronic): 2213-2619

Publisher: Elsevier Ltd

URL: .R S Agbeko PhD, E Day MBBS

DOI: 10.1016/S2213-2600(26)00008-1

Data Access Statement: Data collected for BESS, including de-identified individual participant data, can be made available to researchers who provide a methodologically sound proposal to the Chief Investigator for BESS with a signed data access agreement that is approved by the University of Liverpool as sponsor (sponsor@liverpool.ac.uk).


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Funding

Funder referenceFunder name
Chief Scientist Office in Scotland
Chiesi Farmaceutici
Efficacy and Mechanism Evaluation Programme (NIHR award 15/21/01)
Health and Social Care Research and Development Division in Northern Ireland
NIHR
UKRI Medical Research Council

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