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Lookup NU author(s): Professor David SteelORCiD
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).
© The Author(s) 2026.Purpose: To compare in vitro performance of phacoemulsification platforms during critical surgical phases including aspiration, occlusion and occlusion break. Methods: Five phacoemulsification platforms (Alcon Centurion, Bausch & Lomb PC Stellaris, BVI Virtuoso, DORC Eva Nexus and Zeiss Quatera) underwent standardized testing including controlled occlusion within a collapsible test chamber. Tests were conducted with 21G tips, infusion pressure presets 30 and 55 mmHg, flow-rate 30 ml/min and vacuum range 200–600 mmHg. Outcome measures included Intraocular Pressure (IOP) at rest, during aspiration, occlusion and standardized occlusion break as well as chamber volume loss and time to regain 90% of IOP after/during occlusion break. Results: All devices kept target IOP at rest. During aspiration, IOP changed significantly (p < 0.01): Stellaris showed the greatest IOP reduction, Quatera had small decrease, Virtuoso maintained preset, Centurion and Eva Nexus slightly overcompensated. During occlusion, Eva Nexus and Stellaris PC exceeded the preset 55 mmHg (p < 0.05) whereas other machines remained on target. Upon occlusion break, volume loss ranged 35-200μL (p < 0.001) and recovery time to 90% of preset IOP varied between 0.30–2 s (p < 0.001) with Centurion and Virtuoso outperforming others at 30 mmHg IOP and Centurion, Quatera and Virtuoso at 55 mmHg IOP. Conclusion: Phacoemulsifiers exhibited distinct behaviour under standardized conditions and fluidic settings significantly influenced performance. Surgeon must understand machines’ fluidic to master different platforms.
Author(s): Rossi T, Querzoli G, Deng CP, Deng GR, Parravano M, Placentino L, Dell'Omo R, Steel DH, Romano MR
Publication type: Article
Publication status: Published
Journal: Graefe's Archive for Clinical and Experimental Ophthalmology
Year: 2026
Pages: epub ahead of print
Online publication date: 25/03/2026
Acceptance date: 15/03/2026
Date deposited: 13/04/2026
ISSN (print): 0721-832X
ISSN (electronic): 1435-702X
Publisher: Springer Science and Business Media Deutschland GmbH
URL: https://doi.org/10.1007/s00417-026-07209-0
DOI: 10.1007/s00417-026-07209-0
PubMed id: 41879983
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