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Lookup NU author(s): Dr Christo TsilifisORCiD, Professor Andrew GenneryORCiD
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© 2026 Elsevier LtdOutcomes following solid organ transplantation (SOT) and haematopoietic stem cell transplantation (HSCT) in children and young people continue to improve, yet infections remain a leading cause of morbidity and mortality. Children are particularly vulnerable to infection due to immaturity of the immune system and incomplete vaccination. The risk of infection is governed by graft type, degree of immunosuppression, the time elapsed since transplantation, and for HSCT recipients, immune reconstitution and graft-versus-host disease (GvHD). The pathogens causing infection also vary by interval from transplant, and patient/donor characteristics such as serostatus and colonization with resistant organisms. This review summarises the epidemiology, pathogenesis, and spectrum of infections following paediatric SOT and HSCT.
Author(s): Tsilifis C, Gennery AR
Publication type: Review
Publication status: Published
Journal: Paediatrics and Child Health
Year: 2026
Pages: epub ahead of print
Online publication date: 01/04/2026
Acceptance date: 02/04/2025
ISSN (print): 1751-7222
ISSN (electronic): 1878-206X
Publisher: Churchill Livingstone
URL: https://doi.org/10.1016/j.paed.2026.03.002
DOI: 10.1016/j.paed.2026.03.002
