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Lookup NU author(s): Dr Sue BellassORCiD, Dr Felicity DewhurstORCiD, Nicola HoweORCiD, Dr Sara PretoriusORCiD, Domna Salonen, Freya Thompson
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
The growing prevalence of multiple long-term conditions (MLTC) – two or more long-term health conditions – has been recognised as one of the most significant health challenges facing contemporary societies. People living with MLTC experience poorer outcomes than people with one long-term condition and may be disadvantaged by health care systems configured for single conditions. Recognition of the significance of these inequities has led to increased investments in MLTC research, and a body of qualitative literature on lived experience is developing. However, conducting qualitative MLTC research presents challenges to researchers. Encompassing an extensive range of condition combinations, the MLTC population is incredibly diverse, and constructing a sampling strategy for the small numbers of participants typical in qualitative inquiry requires careful thought. Additionally, MLTC is a construct not embedded in public consciousness, which may affect participant self-identification and research engagement. Furthermore, the risk of issues commonly experienced in qualitative health research, such as participant distress and low recruitment rates, can be exacerbated due to the ill-health experienced by some people living with MLTC. In this article, we share reflections from a cross-institution Qualitative Methods Community of Practice in MLTC Research, describing the challenges experienced and practical steps taken to address difficulties and mitigate risks. We aim to provide tips and guidance to qualitative health researchers new to MLTC inquiry to support planning and delivery of their research in this rapidly growing field.
Author(s): Bellass S, Ellwood A, Arakelyan S, Bowers SP, Dewhurst F, Hanley SJ, Hayanga B, Hopkins SA, Howe N, Hunt E, Lewis G, Lippiett K, McCloskey E, Pretorius S, Salonen D, Shoemark-Sells EZ, Thompson A, Thompson F, Vowles Z, Walker H, Wheat H
Publication type: Article
Publication status: Published
Journal: Journal of Multimorbidity and Comorbidity
Year: 2026
Volume: 16
Pages: 1-11
Online publication date: 10/06/2026
Acceptance date: 29/05/2026
Date deposited: 17/06/2026
ISSN (electronic): 2633-5565
Publisher: Sage Publications Ltd.
URL: https://doi.org/10.1177/26335565261459508
DOI: 10.1177/26335565261459508
Data Access Statement: This is a methods paper rather than a findings paper. We are not reporting empirical data
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