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Lookup NU author(s): Kurchi Mitra, Dr Sophie Butterworth, Jason PowellORCiD
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© The Author(s), 2026. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED.While otitis media with effusion (OME) is well-documented in children with cleft palate +/- lip (CP +/-L), acute otitis media (AOM) is less clearly defined. This paper aims to explore the evidence regarding the prevalence, suggested pathophysiology, and management options for AOM in children with CP +/- L. Methods: A structured literature search was conducted using Medline, Embase and Cochrane databases. 465 records were identified and screened independently. A total of 23 studies were included. Results: There is variability in the reported prevalence of AOM, with some studies suggesting a higher prevalence and extended disease course. The heterogeneity in study design and terminology used to define otitis media in the literature adds to the complexity in interpretation. Various management strategies have been proposed. Evidence of their effectiveness is limited. Further research is warranted to establish evidence-based management pathways, recognising the role of otolaryngologists within cleft multidisciplinary teams.
Author(s): Mitra K, Nair S, Kazi M, Butterworth S, Powell J
Publication type: Review
Publication status: Published
Journal: Journal of Laryngology and Otology
Year: 2026
Pages: Epub ahead of print
Online publication date: 27/07/2026
Acceptance date: 02/04/2018
ISSN (print): 0022-2151
ISSN (electronic): 1748-5460
Publisher: Cambridge University Press
URL: https://doi.org/10.1017/S0022215126105659
DOI: 10.1017/S0022215126105659
PubMed id: 42504799
