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Full Body Embolic Protection During Transcatheter Aortic Valve Replacement in High Risk Patients

Lookup NU author(s): Dr Omran Abukhalaf, Dr Rajiv Das, Dr Mohammad Alkhalil

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).

Abstract

© 2026 The Authors. Stroke remains one of the most feared complications of transcatheter aortic valve replacement (TAVR). We report our initial experience using a dedicated full-body embolic protection device during TAVR in 3 patients with severe aortic stenosis and high-risk embolic features. This included large thrombus on the aortic valve, a left ventricular outflow tract mass, and persistent left atrial thrombus despite anticoagulation. Device deployment and retrieval were successful in all procedures, with no device-related complications or neurologic events at 30-day follow-up. Macroscopic debris was retrieved in 2 patients, and histopathologic analysis in 1 case demonstrated atheromatous plaque components. This initial experience demonstrates the feasibility of full-body embolic protection in selected patients with high-risk undergoing TAVR and supports further evaluation in prospective studies.

Publication metadata

Author(s): Abukhalaf O, Das R, Alkhalil M

Publication type: Article

Publication status: Published

Journal: JACC: Case Reports

Year: 2026

Pages: Epub ahead of print

Online publication date: 13/08/2026

Acceptance date: 06/07/2026

Date deposited: 01/09/2026

ISSN (electronic): 2666-0849

Publisher: Elsevier Inc.

URL: https://doi.org/10.1016/j.jaccas.2026.109800

DOI: 10.1016/j.jaccas.2026.109800

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