The Synthesis and Thymidylate Synthase Inhibitory Activity of L-Gamma-L-Linked Dipeptide and L-Gamma-Amide Analogs of 2- Desamino-2-Methyl-N(10)-Propargyl-5,8-Dideazafolic Acid (Ici- 198583)

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Author(s): Bisset GMF, Bavetsias V, Thornton TJ, Pawelczak K, Calvert AH, Hughes LR, Jackman AL

Publication type: Article

Publication status: Published

Journal: Journal of Medicinal Chemistry

Year: 1994

Volume: 37

Issue: 20

Pages: 3294-3302

Print publication date: 01/09/1994

ISSN (print): 0022-2623

ISSN (electronic): 1520-4804

URL: http://dx.doi.org/10.1021/jm00046a014

DOI: 10.1021/jm00046a014

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