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Neurotransmitter mechanisms of dreaming: Implication of modulatory systems based on dream intensity

Lookup NU author(s): Emeritus Professor Elaine Perry, Dr Margaret Piggott


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Based on increasing dream intensity and alterations in neurophysiological activity from waking, through NREM to REM sleep, dreaming appears to correlate with sustained midbrain dopaminergic and basal forebrain cholinergic, in conjunction with decreasing brainstem 5-HT and noradrenergic neuronal activities. This, model, with features in common with the modulatory transmitter models of Hobson et al. and Solms, is consistent with some clinical observations on drug induced alterations in dreaming and transmitter correlates of delusions.

Publication metadata

Author(s): Perry EK, Piggott MA

Publication type: Article

Publication status: Published

Journal: Behavioral and Brain Sciences

Year: 2000

Volume: 23

Issue: 6

Pages: 990-992

Print publication date: 01/01/2000

ISSN (print): 0140-525X

ISSN (electronic): 1469-1825

Publisher: Cambridge University Press


DOI: 10.1017/S0140525X00774024

Notes: Using Smart Source Parsing (pp


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