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Lookup NU author(s): Dr Julian Venables
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RNA-binding proteins are essential for spermatogenesis: they are required in the nucleus of germ cells, for the production of specific mRNA isoforms, and in the cytoplasm - where proteins required for chromatin condensation and for changes in cell morphology are translated long after transcription ceases. Some of the RNA targets and the RNA-binding proteins themselves have been identified recently. Both nuclear and cytoplasmic proteins are affected in examples of azoospermia in men.
Author(s): Venables JP; Eperon I
Publication type: Article
Publication status: Published
Journal: Current Opinion in Genetics & Development
Print publication date: 13/08/1999
ISSN (print): 0959-437X
ISSN (electronic): 1879-0380
Publisher: Elsevier Ltd
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