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Lookup NU author(s): Professor Zofia Chrzanowska-Lightowlers,
Professor Robert Lightowlers
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Cytochrome c oxidase L-form transcript-binding protein (COLBP) activity parallels the tissue-specific mRNA expression of bovine cytochrome c oxidase liver isopeptides. A similar RNA-binding activity is found in human myoblast and liver Hep G2 cell homogenates. Human COLBP activity, however, is not present in myotubes or adult skeletal muscle. It is proposed that COLBP down-regulation during muscle cell differentiation may underlie oxidase isoform switching during myogenesis.
Author(s): Preiss T, Chrzanowska-Lightowlers ZM, Lightowlers RN
Publication type: Article
Publication status: Published
Journal: Biochimica et Biophysica Acta
Print publication date: 28/04/1994
ISSN (print): 0006-3002
ISSN (electronic): 0005-2728