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The tubulin ancestor, FtsZ, draughtsman, designer and driving force for bacterial cytokinesis

Lookup NU author(s): Dr Stephen Addinall


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We discuss in this review the regulation of synthesis and action of FtsZ, its structure in relation to tubulin and microtubules, and the mechanism of polymerization and disassembly (contraction) of FtsZ rings from a specific nucleation site (NS) at mid cell. These topics are considered in the light of recent immunocytological studies, high resolution structures of some division proteins and results indicating how bacteria may measure their mid cell point.

Publication metadata

Author(s): Addinall SG; Holland B

Publication type: Article

Publication status: Published

Journal: Journal of Molecular Biology

Year: 2002

Volume: 318

Issue: 2

Pages: 219-236

ISSN (print): 0022-2836

ISSN (electronic): 1089-8638

Publisher: Academic Press


DOI: 10.1016/S0022-2836(02)00024-4

Notes: Addinall, Stephen G Holland, Barry Research Support, Non-U.S. Gov't Review England Journal of molecular biology J Mol Biol. 2002 Apr 26;318(2):219-36.


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