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Glycoconjugates of gadolinium complexes for MRI applications

Lookup NU author(s): Professor David Fulton

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Abstract

Examples of C-4 symmetric, medium MW conjugates incorporating 12 glucose or galactose groups linked via four dendritic wedges to a central Gd complex have been characterised; their enhanced relaxivity is interpreted in terms of effective motional coupling and large contributions from second sphere water molecules.

Publication metadata

Author(s): Fulton DA, Elemento EM, Aime S, Chaabane L, Botta M, Parker D

Publication type: Article

Publication status: Published

Journal: Chemical Communications

Year: 2006

Volume: 2006

Issue: 10

Pages: 1064-1066

ISSN (print): 1364-548X

ISSN (electronic): 1364-548X

Publisher: Royal Society of Chemistry

URL: http://dx.doi.org/10.1039/b517997a

DOI: 10.1039/b517997a

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