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Sequencing and functional analysis of the genome of Bacillus subtilis strain 168

Lookup NU author(s): Professor Colin Harwood, Professor Anil Wipat


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The international programme to sequence the 4.2 Mb genome of Bacillus subtilis, a model Gram-positive bacterium, is a joint project involving European, Japanese and US research groups. To date ca. 3.0 Mb of the genome has been sequenced, with the remaining 1.2 Mb expected to be completed in 1997. The amenability of B. subtilis to genetic manipulation, combined with the availability of extensive expertise on its biochemistry and physiology, makes this bacterium a valuable organism in which to investigate the properties of genes for which functions cannot be readily ascribed by standard methods.

Publication metadata

Author(s): Harwood CR, Wipat A

Publication type: Article

Publication status: Published

Journal: FEBS Letters

Year: 1996

Volume: 389

Issue: 1

Pages: 84-87

Print publication date: 24/06/1996

ISSN (print): 0014-5793

ISSN (electronic): 1873-3468

Publisher: Elsevier


DOI: 10.1016/0014-5793(96)00524-8

PubMed id: 8682212


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