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Mitochondrial function in muscle from elderly athletes

Lookup NU author(s): Dr Elizabeth Brierley, Dr Margaret Johnson, Professor Gary Ford, Emeritus Professor Oliver James, Emeritus Professor Doug Turnbull

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Abstract

The extent to which mitochondria are involved in the aging process is controversial; much of the reported decline in mitochondrial oxidations in human skeletal muscle may be due to disease and inactivity rather than age. To study true aging, mitochondrial respiratory chain function was studied in 9 young and 12 elderly athletes. No significant deterioration with age was observed. If mitochondria are involved in aging, it must be through a more subtle mechanism than a global decline in respiratory chain activity.


Publication metadata

Author(s): Brierley EJ, Johnson MA, Bowman A, Ford GA, Subhan F, Reed JW, James OFW, Turnbull DM

Publication type: Article

Publication status: Published

Journal: Annals of Neurology

Year: 1997

Volume: 41

Issue: 1

Pages: 114-116

Print publication date: 01/01/1997

ISSN (print): 0364-5134

ISSN (electronic): 1531-8249

Publisher: Wiley-Blackwell Publishing

URL: http://dx.doi.org/10.1002/ana.410410120

DOI: 10.1002/ana.410410120

PubMed id: 9005875


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