Toggle Main Menu Toggle Search

Open Access padlockePrints

The preparation and coordination chemistry of substituted benzenethiols. Triphenylphosphine gold(I) complexes of sterically demanding and nondemanding arenethiols. The absence of gold(I)-gold(I) interactions

Lookup NU author(s): Emeritus Professor Bill CleggORCiD, Dr Mark Elsegood, Dr Lynne Horsburgh


Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Novel substituted benzenethiols can be easily prepared via aryl thiocyanates or aryl bromides. Reaction of [(Ph3P)AuCl] with the sterically-nondemanding benzenethiols HSC6H4NMe2-p and HSC6H4NMe3+-p and with the sterically-demanding benzenethiols HSCMe2H2NMe2-p, HSC6Me4H-p and in the presence of triethylamine yields the monomeric gold(I) complexes [(Ph3P)Au(SAr)], which are analogous to the gold-based antiarthritic drug Auranofin. Reaction with the sterically demanding dithiol HSC6Me4SH-p in the presence of NEt3 yields the dimeric complex [{(Ph3P)Au}2(μ-SC6Me4S-p)]. Spectrochemical and electrochemical data are reported. The crystal structures of [(Ph3P)Au(SC6H4NMe2-p)] and [(Ph3P)Au(SC6H4NMe3-p)]PF 6 have been solved: both complexes are monomeric in the solid state, lacking the short gold-gold interaction which is commonly found in gold(I) complexes of soft ligands, e.g., [(Ph3P)Au(SPh)]2.

Publication metadata

Author(s): Ahmed LS, Clegg W, Davies DA, Dilworth JR, Elsegood MRJ, Griffiths DV, Horsburgh L, Miller JR, Wheatley N

Publication type: Article

Publication status: Published

Journal: Polyhedron

Year: 1998

Volume: 18

Issue: 3-4

Pages: 593-600

Print publication date: 18/12/1998

ISSN (print): 0277-5387

ISSN (electronic): 1873-3719

Publisher: Pergamon


DOI: 10.1016/S0277-5387(98)00339-8


Altmetrics provided by Altmetric