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Design and synthesis of a novel cyclo-β-tetrapeptide

Lookup NU author(s): Dr Mark Elsegood, Professor Richard Jackson

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Abstract

N-Substituted tetralactams (cyclo-β-tetrapeptides) have been identified as potential molecular scaffolds by computer-aided design; compound 2, arising from L-β-homophenylalanine, has been prepared as a model system and its structure elucidated by single crystal X-ray analysis and NMR spectroscopy.

Publication metadata

Author(s): Sutton PW, Bradley A, Elsegood MRJ, Farras J, Jackson RFW, Romea P, Urpi F, Vilarrasa J

Publication type: Article

Publication status: Published

Journal: Tetrahedron Letters

Year: 1999

Volume: 40

Issue: 13

Pages: 2629-2632

Print publication date: 26/03/1999

ISSN (print): 0040-4039

ISSN (electronic): 1873-3581

Publisher: Pergamon

URL: http://dx.doi.org/10.1016/S0040-4039(99)00234-8

DOI: 10.1016/S0040-4039(99)00234-8

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