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Lookup NU author(s): Dr Clive Ballard, Professor John O'Brien, Dr Alan Swann, Dr David Neill, Professor David BurnORCiD, Emeritus Professor Robert Perry, Professor Ian McKeith
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The progression of parkinsonism over 1 year was evaluated in a prospective cohort of patients (n = 338), suffering from dementia with Lewy bodies (DLB), Alzheimer's disease (AD) or vascular dementia (VaD). Parkinsonism was assessed using the modified Unified Parkinson's Disease Rating Scale. Significant parkinsonism was significantly commoner in DLB sufferers (71%) than amongst patients with AD (7%) or VaD (10%). DLB patients with established parkinsonism had an annual increase in severity of 9%, but progression was more rapid (49% in 1 year) in patients with early parkinsonism. Parkinsonism was frequent at all severities in DLB patients, but usually only present in other dementias when MMSE<10. (C) 2000 S. Karger AG, Basel.
Author(s): McKeith I; Perry R; O'Brien J; Burn D; Ballard C; Swann A; Neill D; Lantos P; Holmes C; Ince P
Publication type: Article
Publication status: Published
Journal: Dementia and Geriatric Cognitive Disorders
Year: 2000
Volume: 11
Issue: 4
Pages: 219-222
Print publication date: 01/01/2000
ISSN (print): 1420-8008
ISSN (electronic): 1421-9824
Publisher: S Karger AG
URL: http://dx.doi.org/10.1159/000017240
DOI: 10.1159/000017240
PubMed id: 10867448
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