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Room temperature palladium-catalysed coupling of amino acid-derived organozinc reagents with aryl triflates

Lookup NU author(s): Professor Richard Jackson

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Abstract

Aryl triflates may be cross-coupled with the amino acid derived zinc reagents 1, 2 and 3 using palladium catalysis at room temperature, in the presence of anhydrous lithium chloride, conveniently yielding phenylalanine 4, β-homophenylalanine 5 and γ-bishomophenylalanine 6 derivatives respectively (nine examples). (C) 2000 Elsevier Science Ltd.

Publication metadata

Author(s): Dexter CS, Jackson RFW, Elliott J

Publication type: Article

Publication status: Published

Journal: Tetrahedron

Year: 2000

Volume: 56

Issue: 26

Pages: 4539-4540

ISSN (print): 0040-4020

ISSN (electronic): 1464-5416

Publisher: Pergamon

URL: http://dx.doi.org/10.1016/S0040-4020(00)00362-8

DOI: 10.1016/S0040-4020(00)00362-8

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