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Regional variation in incidence and case fatality of myocardial infarction among young women in England, Scotland and Wales

Lookup NU author(s): Professor Simon Thomas


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Objectives - To examine the regional variation in incidence and case fatality of myocardial infarction among young women. Design - Cross sectional survey, using population based incidence data. Setting - England, Scotland and Wales. Subjects - Subjects were women aged 16-44 with a diagnosis of myocardial infarction between 1 October 1993 and 15 October 1995. Outcome measures - Incidence of myocardial infarction per 100,000 women years, with case fatality as a percentage of total cases. Results - Incidence of myocardial infarction rose steeply from age 33 upwards, (maximum = 20.2 cases per 100,000 women years at age 44). The adjusted incidence rate for myocardial infarction was 3.7 (95% CI 3.2, 4.2) times greater in Scotland than in southern England. In contrast, case fatality was significantly lower in Scotland: 18.5% (95% CI 13.1%, 25.0%), compared with 31.0% (95% CI 25.9%, 36.0%) in southern England. Conclusions - The incidence of myocardial infarction varied widely within the United Kingdom. Case fatality variation may reflect differences in ambulance response, or in diagnostic acumen, within the regions.

Publication metadata

Author(s): Thomas S; Dunn NR; Arscott A; Thorogood M; Faragher B; De Caestecker L; MacDonald TM; McCollum C; Mann RD

Publication type: Article

Publication status: Published

Journal: Journal of Epidemiology and Community Health

Year: 2000

Volume: 54

Issue: 4

Pages: 293-298

ISSN (print): 0143-005X

ISSN (electronic): 1470-2738

Publisher: BMJ Publishing Group Ltd


DOI: 10.1136/jech.54.4.293

PubMed id: 10827912


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