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Nasal polyposis: Role of subclinical delayed food hypersensitivity

Lookup NU author(s): Emerita Professor Janet WilsonORCiD


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Nasal polyposis is a common problem in otolaryngology. The cause remains unclear, and treatment with medication and surgery is often unsatisfactory. We present our controlled study, which suggests a strong association between food allergy and nasal polyposis. The study was conducted in 2 parts. A postal survey of 900 patients with nasal polyps showed 53 respondents (5.9%) had a known food allergy. In the prospective study, 80 nasal polyp patients and 36 control subjects completed intradermal tests for food allergy. Sixty- five nasal polyp patients (81%) and 4 control subjects (11%) had positive intradermal food test results. This is highly significant. We believe that food allergy may play a significant role in the pathogenesis of nasal polyposis and should be further studied.

Publication metadata

Author(s): Wilson JA; Pang Y-T; Eskici O

Publication type: Article

Publication status: Published

Journal: Otolaryngology - Head and Neck Surgery

Year: 2000

Volume: 122

Issue: 2

Pages: 298-301

Print publication date: 01/01/2000

ISSN (print): 0194-5998

ISSN (electronic): 1097-6817

Publisher: Mosby, Inc.


DOI: 10.1016/S0194-5998(00)70259-2

PubMed id: 10652410


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