Browse by author
Lookup NU author(s): Dr Elizabeth McIntyre, Dr Petros PerrosORCiD
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Case report A 39-year-old man with Type 1 diabetes mellitus was hospitalized with severe diabetic ketoacidosis (DKA). Sixteen hours after admission he suddenly deteriorated having a respiratory then cardiac arrest. A brain computed tomography scan performed 2 h after the respiratory arrest showed severe cerebral oedema. Serial serum samples were stored and analysed for S-100β protein. The S- 100β protein concentration was initially normal (0.12 μg/l) then rose significantly before the onset of the respiratory arrest (8.5 h = 0.61 μg/l, 14.5 h = 0.9 μg/l, 18 h = 1.6 μg/l, 25.5 h = 3.1 μg/l, 34 h = 4.6 μg/l and 44 h = 19.5 μg/l). Conclusions: In this case of DKA, serum S-100β concentration rose coinciding with the onset of cerebral oedema, before it became clinically evident. Monitoring serum S-100β may have a useful role in the management of DKA.
Author(s): McIntyre EA, Abraha HD, Perros P, Sherwood RA
Publication type: Article
Publication status: Published
Journal: Diabetic Medicine
Year: 2000
Volume: 17
Issue: 11
Pages: 807-809
ISSN (print): 0742-3071
ISSN (electronic): 1464-5491
Publisher: Wiley-Blackwell Publishing Ltd.
URL: http://dx.doi.org/10.1046/j.1464-5491.2000.00370.x
DOI: 10.1046/j.1464-5491.2000.00370.x
PubMed id: 11131106
Altmetrics provided by Altmetric
