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Insulin sensitivity and fertility

Lookup NU author(s): Professor Roy Taylor


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This review sets in context significant recent advances in the understanding of the pathophysiology of polycystic ovary syndrome (PCOS). The occurrence of variable insulin sensitivity in individuals is discussed. Information is presented to demonstrate that prolonged anovulation decreases insulin sensitivity and, conversely, that improvement in insulin sensitivity normalizes ovarian function in PCOS. In addition, a meta-analysis of studies on metformin and troglitazone treatment in PCOS is presented.

Publication metadata

Author(s): Taylor R, Marsden PJ

Publication type: Review

Publication status: Published

Journal: Human Fertility

Year: 2000

Volume: 3

Issue: 1

Pages: 65-69

Print publication date: 01/01/2000

ISSN (print): 1464-7273

ISSN (electronic): 1742-8149


PubMed id: 11844356