Toggle Main Menu Toggle Search

Open Access padlockePrints

Effect of severity of disability on survival in north east England cerebral palsy cohort

Lookup NU author(s): Emeritus Professor Allan ColverORCiD


Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Aims - To investigate the effect of motor and cognitive disabilities on the survival of people on the North of England Collaborative Cerebral Palsy Survey, and compare this with other published results. Methods - The cerebral palsy cohort consists of 1960-1990 births in Northumberland, Newcastle, and North Tyneside health districts. Survival and cause of death were analysed in relation to data on birth, disabilities, and a unique measure of the impact of disability. Results - Disability strongly influences survival. More than a third of those with a severe disability die before age 30. Fewer than a third of deaths are attributed to cerebral palsy on death certificates. Of those with severe cognitive disability, 63% live to age 35 (58% with severe ambulatory disability and 53% with severe manual disability), whereas at least 98% without severe disabilities live to age 35. The Life-style Assessment Score (LAS) allows a finer categorisation of impact of disability, and is strongly associated with survival: A ten point increase in LAS is associated with a doubling of the hazard rate. People who had LAS of at least 70, and had survived to age 5 have a 39% chance of dying before age 35. Conclusions - The majority of people with cerebral palsy attain adulthood. There appears to be more variation in survival rates associated with severe disability between regions of England, than between north east England, British Columbia, and California. Instantaneous risks of dying vary widely between England and California. This variation is not obviously attributable to differing rates of severe disability.

Publication metadata

Author(s): Hutton JL, Colver AF, Mackie PC, Rosenbloom L

Publication type: Article

Publication status: Published

Journal: Archives of Disease in Childhood

Year: 2000

Volume: 83

Issue: 6

Pages: 468-474

Print publication date: 01/01/2000

ISSN (print): 0003-9888

ISSN (electronic): 1468-2044

Publisher: BMJ Publishing Group Ltd


DOI: 10.1136/adc.83.6.468

PubMed id: 11087278


Altmetrics provided by Altmetric