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Paternal employment in agriculture and childhood kidney cancer

Lookup NU author(s): Professor Mark PearceORCiD, Professor Louise Parker


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This paper explores the hypothesis that there is an association between risk of childhood kidney cancer and paternal employment in occupations that have potential for exposure to herbicides and/or pesticides. In contrast to a previous study using paternal occupations at the time of the child's death, no significant association was found between such potential paternal exposures (using paternal occupations at the time of the child's birth) and the risk of cancer of the kidney in childhood (OR 0.88, 95% CI 0.20-3.84). In addition, this paper quantifies the extent to which paternal occupational information on death certificates can be used as a proxy for paternal occupation at birth and how such misclassification could affect risk estimates. An example is given showing how a recently reported association between kidney cancer and paternal agricultural employment may have been overestimated as a result of the use of death certificate information.

Publication metadata

Author(s): Pearce MS, Parker L

Publication type: Article

Publication status: Published

Journal: Pediatric Hematology and Oncology

Year: 2000

Volume: 17

Issue: 3

Pages: 223-230

Print publication date: 01/04/2000

ISSN (print): 0888-0018

ISSN (electronic): 1521-0669

Publisher: Informa Healthcare


DOI: 10.1080/088800100276398

PubMed id: 10779988


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