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Stereocontrolled approaches to 2-(2-aminoalkyl)-1-hydroxycyclopropanes

Lookup NU author(s): Professor William Clegg

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Abstract

(1S,2S)-2[(S)-Amino(4-methoxyphenyl)methyl]cyclopropan-1-ol together with a range of racemic 2-(2-aminoalkyl)-1-hydroxycyclopropanes were prepared by a stepwise procedure involving a 1,3-dipolar cycloaddition of a nitrile oxide to a cyclopropene followed by reduction of the derived bicycle. © 2001 Elsevier Science Ltd. All rights reserved.

Publication metadata

Author(s): Baird MS, Huber FAM, Clegg W

Publication type: Article

Publication status: Published

Journal: Tetrahedron

Year: 2001

Volume: 57

Issue: 49

Pages: 9849-9858

ISSN (print): 0040-4020

ISSN (electronic): 1464-5416

Publisher: Pergamon

URL: http://dx.doi.org/10.1016/S0040-4020(01)00996-6

DOI: 10.1016/S0040-4020(01)00996-6

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