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The Newcastle University research output collection, currently available on ePrints, will shortly be moving to a new open repository platform, Figshare. To prepare for the data migration we have paused adding new content to ePrints, and will resume once the new repository is launched. During this time you will continue to have access to ePrints (but no new content will appear). We will share updates here when available.

Synthesis of a 3-aminopiperidin-2,5-dione as a conformationally constrained surrogate of the Ala-Gly dipeptide

Lookup NU author(s): Professor Richard Jackson

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Abstract

The preparation of the Boc-{Ala-Gly}-OBn pseudopeptide 4 is reported. The key intermediate, aminoester 5b, was obtained by a cross-coupling reaction of alaninezinc iodide 6 and the thioester of glycine 9. © 2000 Elsevier Science Ltd.


Publication metadata

Author(s): Estiarte MA, Diez A, Rubiralta M, Jackson RFW

Publication type: Article

Publication status: Published

Journal: Tetrahedron

Year: 2001

Volume: 57

Issue: 1

Pages: 157-161

ISSN (print): 0040-4020

ISSN (electronic): 1464-5416

Publisher: Pergamon

URL: http://dx.doi.org/10.1016/S0040-4020(00)00990-X

DOI: 10.1016/S0040-4020(00)00990-X


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