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Lookup NU author(s): Dr Salma Ayis,
Professor Kate Gould
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This study was a pilot investigation of risk factors for the development of Clostridium difficile toxin-associated diarrhoea and in particular the differential influence of antimicrobial agents. The study was a retrospective case- control design conducted at Freeman Hospital, Newcastle upon Tyne. Cases were inpatients with stool positive C. difficile toxin diarrhoea and two controls were drawn for each case matched for age (+/-5 years) and type of admission (emergency or elective). Using conditional logistic regression analysis, cephalosporins and erythromycin were found to be statistically significantly associated with Clostridium difficile toxin associated-diarrhoea. The results form the basis for designing a larger, prospective study. Copyright © 2001 John Wiley & Sons, Ltd.
Author(s): Aziz EE, Ayis S, Gould FK, Rawlins MD
Publication type: Article
Publication status: Published
Journal: Pharmacoepidemiology and Drug Safety
Print publication date: 01/06/2001
ISSN (print): 1053-8569
ISSN (electronic): 1099-1557
Publisher: John Wiley & Sons
PubMed id: 11760491
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