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From genome to function: Systematic analysis of the soil bacterium Bacillus subtilis

Lookup NU author(s): Professor Colin Harwood, Samuel Crawshaw, Professor Anil Wipat


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Bacillus subtilis is a sporulating Gram-positive bacterium that lives primarily in the soil and associated water sources. Whilst this bacterium has been studied extensively in the laboratory, relatively few studies have been undertaken to study its activity in natural environments. The publication of the B. subtilis genome sequence and subsequent systematic functional analysis programme have provided an opportunity to develop tools for analysing the role and expression of Bacillus genes in situ. In this paper we discuss analytical approaches that are being developed to relate genes to function in environments such as the rhizosphere. Copyright © 2001 John Wiley & Sons, Ltd.

Publication metadata

Author(s): Harwood CR, Crawshaw SG, Wipat A

Publication type: Article

Publication status: Published

Journal: Comparative and Functional Genomics

Year: 2001

Volume: 2

Issue: 1

Pages: 22-24

Print publication date: 01/01/2001

ISSN (print): 1531-6912

ISSN (electronic): 1532-6268

Publisher: Hindawi Publishing Corporation


DOI: 10.1002/cfg.69


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