Toggle Main Menu Toggle Search

Open Access padlockePrints

Crossed acyloin condensation of aliphatic aldehydes

Lookup NU author(s): Dr Alistair Henderson, Emeritus Professor Bernard Golding


Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Crossed acyloins were efficiently prepared by the thiazolium-catalysed condensation of two different unhindered aldehydes, using one mol equivalent of one aldehyde with three mol equivalents of the other. Conversion into the corresponding nonsymmetrical 1,2-dioxime was achieved either by oxidation with bismuth(III) oxide or the Dess-Martin periodinane to give a 1,2-diketone that was then treated with hydroxylamine to give the oxime.

Publication metadata

Author(s): Heck R, Henderson AP, Kohler B, Retey J, Golding BT

Publication type: Article

Publication status: Published

Journal: European Journal of Organic Chemistry

Year: 2001

Issue: 14

Pages: 2623-2627

ISSN (print): 1434-193X

ISSN (electronic): 1099-0690

Publisher: Wiley - VCH Verlag GmbH & Co. KGaA


DOI: 10.1002/1099-0690(200107)2001:14<2623::AID-EJOC2623>3.0.CO;2-1


Altmetrics provided by Altmetric