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Lookup NU author(s): Professor Robert Taylor,
Emeritus Professor Doug Turnbull
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Mitochondrial disorders represent a multitude of clinically heterogeneous diseases in which the genetic abnormality can involve either a mitochondrial or nuclear gene. In addition to inherited defects, somatic mitochondrial DNA mutations have been implicated in the pathogenesis of neurodegenerative disease, cancer and the ageing process. The recent emergence of the first mouse models of mitochondrial disease will provide valuable insights into disease mechanisms and aid the development of realistic therapeutic strategies. © 2001 Elsevier Science Ltd.
Author(s): Taylor RW; Turnbull DM; Schaefer AM
Publication type: Review
Publication status: Published
Journal: Current Opinion in Pharmacology
ISSN (print): 1471-4892
ISSN (electronic): 1471-4973
PubMed id: 11712753