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Do intraoral radial forearm free flaps re-mucosalise and is candida infection relevant?

Lookup NU author(s): Dr Almas Khan, David Cloke, Peter Hodgkinson, Neil McLean


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Eleven patients, with a mean age of 57 years, who had undergone radial forearm flap reconstruction following the excision of intraoral carcinoma, underwent flap biopsy at a mean of 45 months postoperatively. Seven of the patients had received postoperative radiotherapy. In eight patients the clinical appearance of the flap was similar in colour to that of adjacent normal oral mucosa; the remaining flaps retained the appearance of normal volar forearm skin. Histological examination of the flaps showed varying degrees of telangiectasia and mild chronic inflammation. In only two patients was superficial infection by candida hyphae identified. Intraoral free flaps, although clinically resembling oral mucosa, retain histological features of skin, at least within the period under study. The erythematous clinical appearance was not correlated with the presence of chronic fungal infection, but reflected the presence of vascular repair tissue, telangiectasia and mild residual chronic inflammation. © 2001 The British Association of Plastic Surgeons.

Publication metadata

Author(s): McLean NR; Cloke DJ; Khan AL; Hodgkinson PD; Soames JV

Publication type: Article

Publication status: Published

Journal: British Journal of Plastic Surgery

Year: 2001

Volume: 54

Issue: 4

Pages: 299-302

Print publication date: 01/01/2001

ISSN (print): 0007-1226

ISSN (electronic): 1465-3087

Publisher: Churchill Livingstone


DOI: 10.1054/bjps.2001.3574

PubMed id: 11355983


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