ePrints

A roundabout route to gene therapy

Lookup NU author(s): Emeritus Professor Doug Turnbull, Professor Robert Lightowlers

Downloads

Full text for this publication is not currently held within this repository. Alternative links are provided below where available.

Abstract

The uniqueness of the mitochondrial genome presents a number of obstacles to the successful use of gene therapy for the treatment of mitochondrial DNA disease. A new study shows that the effects of a pathogenic mutation in a human mitochondrial gene can be rectified by expressing an engineered wildtype copy of the gene in the nucleus.

Publication metadata

Author(s): Turnbull DM, Lightowlers RN

Publication type: Note

Publication status: Published

Journal: Nature Genetics

Year: 2002

Volume: 30

Issue: 4

Pages: 345-346

Print publication date: 01/04/2002

ISSN (print): 1061-4036

ISSN (electronic): 1546-1718

URL: http://dx.doi.org/10.1038/ng0402-345

DOI: 10.1038/ng0402-345

PubMed id: 11925553

Share