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The Newcastle University research output collection, currently available on ePrints, will shortly be moving to a new open repository platform, Figshare. To prepare for the data migration we have paused adding new content to ePrints, and will resume once the new repository is launched. During this time you will continue to have access to ePrints (but no new content will appear). We will share updates here when available.

A high yielding route to substituted piperidines via the aza-Diels-Alder reaction

Lookup NU author(s): Professor William Clegg

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Abstract

The imine Ph2CHN=CHCO2Et, generated from benzhydrylamine and ethyl glyoxylate, is an excellent dienophile in aza-Diels-Alder reactions, giving diastereomerically pure cycloadducts in high yield. © 2002 Elsevier Science Ltd. All rights reserved.

Publication metadata

Author(s): Bailey PD, Smith PD, Pederson F, Clegg W, Rosair GM, Teat SJ

Publication type: Article

Publication status: Published

Journal: Tetrahedron Letters

Year: 2002

Volume: 43

Issue: 6

Pages: 1067-1070

ISSN (print): 0040-4039

ISSN (electronic): 1873-3581

Publisher: Pergamon

URL: http://dx.doi.org/10.1016/S0040-4039(01)02148-7

DOI: 10.1016/S0040-4039(01)02148-7

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