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Genes that shape the course of ageing

Lookup NU author(s): Emeritus Professor Thomas Kirkwood


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Recent discoveries have placed the insulin signalling pathways at the heart of the genetic control of longevity. An elegant new study of genes acting downstream of these signals in the nematode worm Caenorhabditis elegans reveals a plethora of information about the complex network of mechanisms that modulate the ageing process.

Publication metadata

Author(s): Kirkwood TBL

Publication type: Review

Publication status: Published

Journal: Trends in Endocrinology and Metabolism

Year: 2003

Volume: 14

Issue: 8

Pages: 345-347

Print publication date: 01/10/2003

ISSN (print): 1043-2760

ISSN (electronic): 1879-3061


DOI: 10.1016/j.tem.2003.08.003

PubMed id: 14516929