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1-tert-Butyl 2-methyl 4-(R)-hydroxy-pyrrolidine-1,2-(2S)-dicarboxylate

Lookup NU author(s): Emeritus Professor Bill CleggORCiD, Herve Deboves, Dr Mark Elsegood


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The title compound, C11H19NO5, is a protected derivative of trans-4-hydroxy-L-proline. The pyrrolidine ring has a twisted conformation. The N atom has planar coordination and is conjugated with the attached ester group. The methyl ester substituent is pseudo-equatorial, while the hydroxy group is pseudo-axial and acts as a hydrogen-bond donor to a carbonyl O atom in an adjacent molecule, forming molecular chains. © 2003 International Union of Crystallography Printed in Great Britain - all rights reserved.

Publication metadata

Author(s): Clegg W, Deboves HJC, Elsegood MRJ

Publication type: Article

Publication status: Published

Journal: Acta Crystallographica Section E: Structure Reports Online

Year: 2003

Volume: 59

Issue: 12

Pages: o1987-o1989

Print publication date: 01/12/2003

ISSN (print): 1600-5368

ISSN (electronic):

Publisher: Wiley-Blackwell Publishing


DOI: 10.1107/S1600536803026412


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