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Lookup NU author(s): Professor Colin Ingram
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In the bed nuclei of the stria terminalis (BST), opioids may suppress the facilitatory effect of oxytocin on its own release pre-partum. In vitro electrophysiological recording showed that in virgin, late-pregnant, and lactating rats, a δ-opioid agonist inhibited a high proportion of BST neurons, many of which were also oxytocin responsive. Response magnitude did not differ significantly between groups, suggesting that the postulated pre-partum increase in opioid tone does not involve postsynaptic changes in neuronal sensitivity. © 2003 Elsevier B.V. All rights reserved.
Author(s): Wilson BC, Ingram CD
Publication type: Article
Publication status: Published
Journal: Brain Research
ISSN (print): 0006-8993
ISSN (electronic): 1872-6240
PubMed id: 14575903
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