Toggle Main Menu Toggle Search

Open Access padlockePrints

Long-term immunologic effects of alemtuzumab: Immune reconstitution and immune function after alemtuzumab therapy for autoimmune disease

Lookup NU author(s): Professor John IsaacsORCiD


Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


In summary, alemtuzumab resulted in profound and prolonged lymphopenia, particularly affecting CD4+ T cells in a variety of autoimmune conditions. Critically, long-term follow-up data of more than 200 patients showed that alemtuzumab therapy was not associated with an obvious increase in morbidity or mortality.

Publication metadata

Author(s): Isaacs JD

Publication type: Article

Publication status: Published

Journal: Transplantation Reviews

Year: 2003

Volume: 17

Issue: 4 (suppl. 1)

Pages: S12-S15

ISSN (print): 0955-470X

ISSN (electronic): 1557-9816

Publisher: WB Saunders Co.


DOI: 10.1016/j.trre.2003.07.006


Altmetrics provided by Altmetric