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Intestinal M cells and their role in bacterial infection

Lookup NU author(s): Dr Ann Clark


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M cells are located in the epithelia overlying mucosa-associated lymphoid tissues such as Peyer's patches where they function as the antigen sampling cells of the mucosal immune system. Paradoxically, some pathogens exploit M cells as a route of invasion. Here we review our current knowledge of intestinal M cells with particular emphasis on the mechanisms underlying bacterial infection of these atypical epithelial cells.

Publication metadata

Author(s): Clark MA, Jepson MA

Publication type: Review

Publication status: Published

Journal: International Journal of Medical Microbiology

Year: 2003

Volume: 293

Issue: 1

Pages: 17-39

Print publication date: 01/04/2003

ISSN (print): 1438-4221

ISSN (electronic): 1618-0607


DOI: 10.1078/1438-4221-00242

PubMed id: 12755364